The mammalian kidney is a complex organ, maintaining the water and nutrient balance of the body. Current knowledge of the essential functions, and the interplay with metabolic processes, are mainly derived from small animal experiments (uni-papilary kidneys) using invasive methods and lacking spatial resolution. The approach presented here addresses these limitations, by introducing a new MR compatible kidney perfusion device, enabling imaging of the underlying metabolic and functional patterns associated with the multi-papillary porcine kidney, better resembeling the human physiology.
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