Meeting Banner
Abstract #4347

­­To evaluate the role of APT-w contrast, optimized for normalization and ROIs selection, in differentiating Infective and Neo-plastic Mass Lesions

Ayan Debnath1,2, Rakesh Kumar Gupta3, Dinil Sasi1, Snekha Thakran1, and Anup Singh1,4

1Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India, 2Center for Magnetic Resonance & Optical Imaging, University of Pennsylvania, Philadelphia, PA, United States, 3Department of Radiology, Fortis Memorial Research Institute, Gurgaon, Haryana, India, 4Department of Biomedical Engineering, All India Institute of Medical Science, New Delhi, India

Differentiation of intra-cranial-mass-lesions (ICMLs), particularly infective vs neoplastic is difficult using conventional MRI. In the current study, the potential of amide proton transfer weighted (APT-w) contrast for differentiating infective and neo-plastic-mass-lesions has been investigated. APT-w contrast was computed and optimized with respect to different types of normalizations and region-of-interests (ROIs) selection. There was substantial overlap of APT-w contrast values among ICMLs. Different normalizations showed significant difference (P<0.05) in differentiating various groups among ICMLs. Histogram analysis played an important role in significant differentiation (P<0.05) of ICMLs. Thus, APT-MRI can enhance diagnostic accuracy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract E-Poster Video

Keywords