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Abstract #4356

Qualitative and quantitative morphology/metabolism analysis of infantile spasms using PET/MR and efficacy evaluation of ACTH therapy

Haodan Dang1, Jiajin Liu1, Honghong Liu1, Liping Zou2, Xiang Feng3, Mu Lin4, Jiahe Tian1, and Baixuan Xu1

1Nuclear medicine, the general hospital of people liberation army, PLA hospital, Beijing, China, 2Pediatrics, the general hospital of people liberation army, PLA hospital, Beijing, China, 3MR Scientific Marketing,Diagnostic Imaging,Siemens Healthcare. Beijing, P.R. China, Beijing, China, 4MR Collaboration,Diagnostic Imaging,Siemens Healthcare. Shanghai, P.R. China, Shanghai, China

This study aimed to investigate the diagnostic performance of positron emission tomography/magnetic resonance imaging (PET/MR) for structural/metabolic abnormality in infantile spasms. We evaluated both the morphology and parameters of PET/MR images by qualitative and quantitative assessment. Our results showed quantitative analysis of PET/MR images could improve the diagnosis of etiologic abnormality. Furthermore, the classification of etiology using PET/MR can indicate the efficacy of adrenocorticotropic hormone (ACTH) treatment and provide valuable information for surgery plan.

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