This study aimed to investigate the diagnostic performance of positron emission tomography/magnetic resonance imaging (PET/MR) for structural/metabolic abnormality in infantile spasms. We evaluated both the morphology and parameters of PET/MR images by qualitative and quantitative assessment. Our results showed quantitative analysis of PET/MR images could improve the diagnosis of etiologic abnormality. Furthermore, the classification of etiology using PET/MR can indicate the efficacy of adrenocorticotropic hormone (ACTH) treatment and provide valuable information for surgery plan.
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