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Abstract #4454

The traveling heads 2.0: Reproducibility of quantitative imaging methods at 7 Tesla

Maximilian N Voelker1,2, Oliver Kraff1, Steffen Goerke3, Frederik B Laun4, Kerrin J Pine5, Philipp Ehses6, Moritz Zaiss7, Andrzej Liebert4, Sina Straub3, Korbinian Eckstein8, Simon Robinson8, Armin M Nagel3,4, Oliver Speck9,10, Mark E Ladd1,3, and Harald H Quick1,2

1Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany, 2High-Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 3Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 4Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, 5Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 6German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 7Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 8High Field MR Center, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 9Otto-von-Guericke-University Magdeburg, Magdeburg, Germany, 10Leibniz Institute for Neurobiology, Magdeburg, Germany

The “traveling heads” is a study to assess the comparability and reproducibility of multicenter human brain imaging at 7T. In previous experiments, we compared typical UHF sequences for structural brain imaging. In this study, we focus on the reproducibility of quantitative imaging and compare methods for volumetry, relaxometry, QSM and CEST between different sites. In addition, three generations of 7T MR systems are compared, i.e. the older installed base consisting of passively and actively shielded magnets of the first and second generation, respectively, as well as the most recent generation which has been approved as a medical device.

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