Abstract #4456

Inter-site Reproducibility of Cardiac Magnetic Resonance Fingerprinting T1 and T2 Quantification in the ISMRM/NIST MRI System Phantom and Human Heart

Yuchi Liu¹, Luuk H.G.A. Hopman², Jesse Hamilton¹, Elizabeth Hillier², Matthias Friedrich², and Nicole Seiberlich^1,3

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Research Institute of the McGill University Health Center, Montreal, QC, Canada, ³Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States

Cardiac Magnetic Resonance Fingerprinting (cMRF) is a novel technique for simultaneous T₁ and T₂ quantification in the myocardium. Because cMRF has the potential to take heart rate variations and any variable system properties into account, it is hypothesized that cMRF will enable more reproducible measurements of T₁ and T₂. The purpose of this study is to evaluate the inter-site reproducibility of cMRF. Excellent agreement of cMRF measurements between two sites (University Hospitals Cleveland Medical Center, Cleveland, US and McGill University Health Center, Montreal, CA) was achieved in the ISMRM/NIST phantom and in the hearts of healthy subjects.

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