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Abstract #4905

Gradient echo modelling with macroscopic field variations and large flip angles

Martin Soellradl1, Stefan Ropele1, and Christian Langkammer1

1Department of Neurology, Medical University of Graz, Graz, Austria

The signal decay of a 2D gradient echo sequence is substantially influenced by macroscopic field variations along the slice profile. Here we propose a numerical model describing the signal decay due to a macroscopic field gradient for arbitrary excitation pulses with large flip angles. Phantom and in-vivo experiments show that accurate modelling requires inclusion of the phase along the slice profile and the polarity of the slice selection gradient. Additionally, we show that applying the model yields better results for R2*-mapping and myelin water fraction estimation.

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