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Abstract #4914

Investigating the Influence of Adipose Fat on the Inhomogeneous Magnetization Transfer (ihMT) Images

Ece Ercan1, Gopal Varma2, Ivan E. Dimitrov3,4, Marco C. Pinho1,3, Shu Zhang1, Xinzeng Wang1, Ananth Madhuranthakam1,3, David C. Alsop2, Robert E. Lenkinski1,3, and Elena Vinogradov1,3

1Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 4Philips Healthcare, Gainesville, FL, United States

Inhomogeneous Magnetization Transfer (ihMT) imaging is a novel enhanced magnetization transfer technique. In this study, we investigated the influence of fat (i.e. adipose tissue) and echo time on the ihMT ratio through simulation, phantom, and in vivo studies. A substantial variation on the ihMTR values in the presence of fat is illustrated, depending on the echo times used.

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