Abstract #4914

Investigating the Influence of Adipose Fat on the Inhomogeneous Magnetization Transfer (ihMT) Images

Ece Ercan¹, Gopal Varma², Ivan E. Dimitrov^3,4, Marco C. Pinho^1,3, Shu Zhang¹, Xinzeng Wang¹, Ananth Madhuranthakam^1,3, David C. Alsop², Robert E. Lenkinski^1,3, and Elena Vinogradov^1,3

¹Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ³Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ⁴Philips Healthcare, Gainesville, FL, United States

Inhomogeneous Magnetization Transfer (ihMT) imaging is a novel enhanced magnetization transfer technique. In this study, we investigated the influence of fat (i.e. adipose tissue) and echo time on the ihMT ratio through simulation, phantom, and in vivo studies. A substantial variation on the ihMTR values in the presence of fat is illustrated, depending on the echo times used.

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