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Abstract #4916

Reproducibility of inhomogeneous magnetization transfer (ihMT): a test-retest, multi-site study

Lei Zhang1, Huipeng Ren1, Qing Fan1, Xiaocheng Wei2, and Zhuanqin Ren1

1Baoji Center Hospital, Baoji, China, 2GE Healthcare China, Beijing, China

Derived from conventional magnetization transfer, inhomogeneous magnetization transfer (ihMT) has been shown to be a promising method for myelin imaging in recent studies. In the present study, the test-retest reproducibility and multi-site variability of ihMT in measuring major white matter fibers were evaluated. Good test-retest reproducibility and multi-site agreements were obtained. These findings support the use of ihMT measurements as biomarkers in multicenter and/or longitudinal studies.

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