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Abstract #4942

Correlation and frequency based analyses between functional QSM and fMRI

Pinar S Ozbay1, Lars Kasper2, Burak Akin3, Klaas P Pruessmann2, and Daniel Nanz4

1NINDS, NIH, Bethesda, MD, United States, 2Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland, 3Department of Radiology, Medical Physics, Medical Center ‐ University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 4Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Zurich, Switzerland

Earlier works demonstrated applications of Quantitative Susceptibility Mapping (QSM) in functional MRI, including both task- and resting-state experiments. The focus had been mostly on the bi-directional activations consistently observed in fQSM. In this work, our aim was to compare the temporal and frequency characteristics of susceptibility and magnitude time-course signals. Importantly, we also included cardiac and respiration signals, and showed that the global susceptibility signal might inherently include more physiological information than the magnitude.

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