Abstract #4942

Correlation and frequency based analyses between functional QSM and fMRI

Pinar S Ozbay¹, Lars Kasper², Burak Akin³, Klaas P Pruessmann², and Daniel Nanz⁴

¹NINDS, NIH, Bethesda, MD, United States, ²Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland, ³Department of Radiology, Medical Physics, Medical Center ‐ University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ⁴Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Zurich, Switzerland

Earlier works demonstrated applications of Quantitative Susceptibility Mapping (QSM) in functional MRI, including both task- and resting-state experiments. The focus had been mostly on the bi-directional activations consistently observed in fQSM. In this work, our aim was to compare the temporal and frequency characteristics of susceptibility and magnitude time-course signals. Importantly, we also included cardiac and respiration signals, and showed that the global susceptibility signal might inherently include more physiological information than the magnitude.

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