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Abstract #4947

Assessment of Hepatic Perfusion Before and After a Meal Challenge Using Pseudo-Continuous Arterial Spin Labeling in MRI: Comparison with Intravoxel Incoherent Motion and Phase Contrast

Saori Watanabe1, Takashi Hamaguchi1, Naoki Ohno2, Yudai Shogan1, Yu Ueda3, Tadanori Takata1, Satoshi Kobayashi1,2,4, Tosiaki Miyati2, and Toshifumi Gabata4

1Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan, 2Faclty of Health Sciences, Institute of Medical, Pharmaceutial and Health Sciences, Kanazawa University, Kanazawa, Japan, 3Philips Japan, Tokyo, Japan, 4Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan

To assess hepatic blood flow (HBF) with a noninvasive method, we acquired HBF flow before and after meal ingestion using the pCASL method. In addition, we investigated the relationship of HBF, perfusion-related diffusion coefficient (D*) with intravoxel incoherent motion and portal vein blood flow (PVBF) with phase contrast. For each value of HBF, D*, and PVBF following meal ingestion increased significantly compared with the values prior to ingestion. However, there were no correlations between hepatic blood flow, perfusion-related diffusion coefficient, or portal flow with either pre- or post-ingestion.

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