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Abstract #4948

Influence of labeling parameters of velocity selective arterial spin labeling for renal perfusion imaging

Isabell K. Bones1, Suzanne L. Franklin1,2, Anita A. Harteveld1, Matthias J.P. van Osch2, Jeroen Hendrikse3, Chrit Moonen1, Marijn van Stralen1, and Clemens Bos1

1Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 2C.J.Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands, 3Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands

Velocity selective arterial spin labeling (VSASL) is a spatially non-selective method that labels spins based on their flow velocity, thereby labeling closer to the target tissue, reducing the influence of arterial transit time (ATT) and requiring no planning. In the abdomen, motion and complex vascular anatomy might, however, require dedicated VS-labeling parameters. We assessed the feasibility of VSASL for renal perfusion measurement by investigating its dependency on essential labeling parameters, and by comparing it with pseudo-continuous ASL (pCASL) as a spatially-selective reference ASL-technique. Our results show, that with carefully chosen sequence parameters, VSASL is feasible for renal perfusion measurement.

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