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Abstract #4954

Optimization of Pseudo Continuous Arterial Spin Labeling for renal ASL

Rebeca Echeverria-Chasco1, Marta Vidorreta2, Verónica Aramendía-Vidaurreta1, Gorka Bastarrika1, and María A. Fernández-Seara1

1Radiology, Clinica Universidad de Navarra, Pamplona, Spain, 2Siemens Healthineers, Madrid, Spain

Arterial Spin Labeling (ASL) is a non-contrast MR perfusion imaging technique. Pseudo continuous ASL (pCASL) is one of its recomended implementations. The efficiency of pCASL has been shown to be dependent on velocity and magnetic field variations. pCASL was assessed through simulations for the measured velocities in the aorta and including off-resonance effects. Five volunteers were imaged with different average gradient to ratio combinations. The results showed that aorta velocities and off-resonance effects shifted the efficiency towards lower ratios and to a constrained smaller range of gradients. A p-value of 0.04 demonstrated that differences in efficiency were significant across Gave values.

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