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Abstract #4956

Implementation and validation of ASL perfusion measurements for population-based imaging

Esther Warnert1, Rebecca Steketee1, Meike Vernooij1,2, Mika Vogel3, Juan-Antonio Hernandez-Tamames1, and Gyula Kotek1

1Radiology & Nuclear Medicine, Erasmus Medical Centre, Rotterdam, Netherlands, 2Epidemiology, Erasmus MC, Rotterdam, Netherlands, 3Global Research, General Electric, Munich, Germany

Pseudocontinuous ASL (pCASL) is an ideal tool for non-invasive perfusion measurements in population-based imaging studies, which require longitudinal scanning with an unchanging MRI hardware and software set-up. Herein we present the results of the implementation and validation of a 3D pCASL sequence for use in the Rotterdam Study, running since 2005.

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