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Abstract #4973

Time efficient T1 measurement of Cortical Bone using a Three-Dimensional Ultrashort Echo Time Cones Variable Flip Angle-Actual Flip Angle Imaging (3D UTE-Cones VFA-AFI) method

Zepeng Wang1,2, Yajun Ma1, Lidi Wan1, Saeed Jerban1, Yanjun Chen1, Eric Chang1,3, and Jiang Du1

1Department of Radiology, University of California, San Diego, San Diego, CA, United States, 2Department of Biomedical Engineering, Tsinghua University, Beijing, China, 3Radiology Service, San Diego Healthcare System, San Diego, CA, United States

To reduce scan time and maintain the accuracy of T1 measurement for cortical bone, we propose a novel T1 measurement approach using three-dimensional ultrashort echo time cones variable flip angle (3D UTE-Cones VFA) with actual flip angle imaging (AFI) technique for the correction of B1 inhomogeneity. The results show the similar bone T1 values were obtained by the proposed fast 3D UTE-Cones AFI-VFA method compared with the previous UTE-Cones AFI and variable TR method.

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