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Abstract #4975

The echo time of balanced steady-state free precession readouts modulates the influence of fat on MOLLI T1 measurements

Ferenc Emil Mozes1, Elizabeth Mary Tunnicliffe1, and Matthew David Robson1,2

1Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom, 2Perspectum Diagnostics, Oxford, United Kingdom

With the increasing world-wide prevalence of non-alcoholic fatty liver disease it is essential to look for non-invasive diagnostic and monitoring methods, like T1 mapping. It has previously been shown that the presence of fat can artificially prolong liver T1 times measured with modified Look-Locker methods. However, this effect depends on the chosen TR and TE of the readout sequence. Since achievable TR and TE differs for scanner vendors and models, it is important to understand the influence of sequence timings on MOLLI T1 measurements in the presence of fat.

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