Abstract #4976

Silent T1-Mapping at 7T Using the Variable Flip Angle Method

Emil Ljungberg^1,2, Brian Burns³, Peder E. Z. Larson⁴, Shannon Kolind⁵, Mark Symms⁶, Florian Wiesinger⁷, and Gareth J Barker¹

¹Neuroimaging, King's College London, London, United Kingdom, ²General Electric Healthcare, London, United Kingdom, ³ASL West, General Electric Healthcare, Menlo Park, CA, United States, ⁴Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ⁵Medicine, University of British Columbia, Vancouver, BC, Canada, ⁶ASL Europe, General Electric Healthcare, Amersham, United Kingdom, ⁷ASL Europe, General Electric Healthcare, Munich, Germany

In this work we present quantitative T₁-maps obtained using the silent, zero echo-time, RUFIS sequence at 7T. Four flip angles (2,4,8,11)° were acquired in 5 minutes. The obtained T₁-maps showed strong contrast between white matter (T₁=1.6s) and cortical grey matter (T₁=2.3s), in agreement with values in the literature. Reduced contrast was observed in deep grey matter structures, attributed to large B₁⁺-errors in the centre of the brain.

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