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Abstract #0096

Fetal whole-heart 4D blood flow MRI with self-calibrated k-t SENSE

Thomas A Roberts1, Joshua FP van Amerom1,2, Lucilio Cordero-Grande1, Alena Uus1, Anthony N Price1, David FA Lloyd1,3, Laurence H Jackson1, Milou PM van Poppel1, Kuberan Pushparajah3, Mary A Rutherford1, Reza Rezavi1,3, Maria Deprez1, and Joseph V Hajnal1
1School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, 2Division of Pediatric Cardiology, The Hospital for Sick Children, Toronto, ON, Canada, 3Department of Congenital Heart Disease, Evelina Children's Hospital, London, United Kingdom

Measurement of blood flow in the fetal heart and the great vessels is challenging due to fetal motion and its small size. Previously, we demonstrated use of k-t SENSE real-time 2D imaging combined with slice-to-volume registration to reconstruct 4D velocity cine volumes. This required 50% of the examination to be spent acquiring training data. In this work we combine sliding window reconstruction of the under-sampled target data with some prior knowledge to dispense with training data altogether. We reconstruct 4D blood flow volumes in 5 fetal hearts using both methods and show that they are broadly equivalent.

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