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Abstract #0162

Fast Whole-Brain MR Elastography Using 3D GRE Multishot Variable Density Spiral Staircase Acquisition

Xi Peng1, Yi Sui1, Sandeep Ganji2, Ashley Anderson2, John Huston1, Richard Ehman1, and James Pipe1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2Philips Healthcare, Gainesville, FL, United States

This work reports a new method for fast whole-brain MRE using a 3D gradient-echo multishot variable-density spiral staircase acquisition. The proposed method enables high-resolution MRE by exploiting the inherently improved through-plane parallel imaging. The displacement-SNR is further enhanced by exploiting a motion encoding gradient of a 2 wave-period duration. Constrained reconstruction and deblurring method are used to generate high-quality spiral images. By integrating all these features, the proposed technique provides flexible trade-off among SNR, resolution, spatial blurring and scan time. In vivo experiments have demonstrated the capability of the proposed method for high-SNR high-resolution MRE in less than 5 minutes.

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