Meeting Banner
Abstract #0163

Model-based heterogenous transverse isotropic MR elastography inversion for brain tissue with aligned fiber tracts

Matthew Mcgarry1, Elijah Van Houten2, Damian Sowinski1, Philip Bayly3, Daniel Smith4, Curtis Johnson4, John Weaver1,5, and Keith Paulsen1,5
1Dartmouth College, Hanover, NH, United States, 2Université de Sherbrooke, Sherbrooke, QC, Canada, 3Washington University in St Louis, St Louis, MO, United States, 4University of Delaware, Newark, DE, United States, 5Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States

An implementation of a transverse isotropic model with fiber directions defined by DTI was added to our finite element model-based nonlinear inversion MRE platform. The algorithm can recover accurate images of complex valued shear modulus, shear anisotropy, and tensile anisotropy from a realistic brain simulation. In vivo application to multi-excitation brain MRE data produced promising results, maintaining high quality images for the base shear modulus and damping ratio, while recovering additional images of anisotropy which may be useful for characterizing diseases affecting white matter tracts or muscle.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords