Abstract #0238

Growth Charting of Grey Matter and White Matter Functional Network among Normal Children and Adolescents

Xuan Bu¹, Kaili Liang¹, Yingxue Gao¹, Lu Lu¹, Hailong Li¹, Lianqing Zhang¹, Shi Tang¹, Yanlin Wang¹, Xinyu Hu¹, Qiyong Gong¹, Bharat Biswal², and Xiaoqi Huang¹

¹Huaxi MR Research Center (HMRRC), Functional and molecular imaging Key Laboratory of Sichuan Province, Department of Radiology, Sichuan University, Chengdu, China, ²Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, United States

In current study, we used a network growth charting method to map the normative maturational trajectories of major functional network activity in both grey matter and white matter. A quadratic maturation trajectory of functional activity was observed in DMN, SMN and FPN for both grey matter and white matter. The coherent maturational trajectory between these grey matter and white matter network suggests the corresponding refinements of brain network function plays an important role in improvements in higher-order cognitive abilities during normative adolescent development.

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