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Abstract #0373

Adiabatic multiband inversion for simultaneous acquisition of 1H MR spectra from two voxels in-vivo at very short echo times

Layla Tabea Riemann1, Christoph Stefan Aigner1, Rüdiger Brühl1, Semiha Aydin1, Ralf Mekle2, Sebastian Schmitter1, Bernd Ittermann1, and Ariane Fillmer1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Germany, 2Center for Stroke Research Berlin, Charité-Universitätsmedizin, Berlin, Germany

In this work, a novel 1H MR spectroscopy sequence is proposed that provides the advantages of single voxel spectroscopy, such as high spectral bandwidth, a narrower point spread function, shorter measurement time and larger signal-to-noise-ratio, as compared to spectroscopic imaging while exciting more than one voxel. A multi-band adiabatic RF pulse was implemented into a SPECIAL sequence to simultaneously acquire the signal of two disjunct voxels at short echo times. The overlapping signal was decomposed using the SENSE algorithm. The new sequence was validated using a two-compartment phantom and its feasibility for in-vivo application is demonstrated at 7 T.

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