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Abstract #0407

Long‑Term Monitoring of Brain Tumors Using MR Metabolic Phenotyping

Eduardo Coello1, Raymond Huang1, Molly F. Charney1, Wufan Zhao1, Huijun Liao1, Changho Choi2, and Alexander Lin1
1Radiology, Brigham and Women's Hospital, Boston, MA, United States, 2Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States

This work introduces the concept of MR metabolic phenotyping (MRMP), a method that combines the high-resolution anatomical context of MRI and the highly specific metabolic information of MR spectroscopic imaging via unsupervised learning. The value of this technique was shown for the long‑term follow up of IDH‑mutated low‑grade gliomas where high sensitivity to changes in the metabolic composition of the major tissue compartments was achieved.

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