A new sequence design was used to combine the CEST saturation method with traditional MRS. Using non-water suppressed metabolite-cycled spectroscopy offers the time-saving simultaneous recording of the traditional CEST z-spectrum and the metabolite spectrum under frequency selective saturation and allows the detection of exchange and magnetization transfer effects on metabolites and macromolecules. This technique might offer additional possibilities for quantifying the metabolite and macromolecular content or give further insight into the composition of the traditional CEST z-spectrum and is also relevant for judging the influence of water-suppression on absolute metabolite signals.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords