Abstract #0528

Short T1 Measurement Using an Inversion Recovery Prepared Three-Dimensional Ultrashort Echo Time Cones (3D IR-UTE-Cones) Method

Zhao Wei^1,2,3, Yajun Ma¹, Hyungseok Jang¹, Wenhui Yang³, and Jiang Du¹

¹Department of Radiology, UC San Diego, San Diego, CA, United States, ²University of Chinese Academy of Sciences, Beijing, China, ³Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China

In magnetic resonance imaging (MRI), T₁ is an important biomarker for many diseases and plays a key role in affecting image contrast. We propose a novel T₁ measurement method combining adiabatic inversion recovery with 3D ultrashort echo time cones pulse sequences (3D IR-UTE-Cones). This study aimed to verify the feasibility of using 3D IR-UTE-Cones to accurately calculate T₁s of short T₂* tissues. The results indicated that this method could precisely measure a broad range of T₁s and that it performed better than commonly used clinical protocols in ultrashort T₁ measurement.

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