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Abstract #0528

Short T1 Measurement Using an Inversion Recovery Prepared Three-Dimensional Ultrashort Echo Time Cones (3D IR-UTE-Cones) Method

Zhao Wei1,2,3, Yajun Ma1, Hyungseok Jang1, Wenhui Yang3, and Jiang Du1
1Department of Radiology, UC San Diego, San Diego, CA, United States, 2University of Chinese Academy of Sciences, Beijing, China, 3Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China

In magnetic resonance imaging (MRI), T1 is an important biomarker for many diseases and plays a key role in affecting image contrast. We propose a novel T1 measurement method combining adiabatic inversion recovery with 3D ultrashort echo time cones pulse sequences (3D IR-UTE-Cones). This study aimed to verify the feasibility of using 3D IR-UTE-Cones to accurately calculate T1s of short T2* tissues. The results indicated that this method could precisely measure a broad range of T1s and that it performed better than commonly used clinical protocols in ultrashort T1 measurement.

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