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Abstract #0575

Post-NAC evaluation using ultrafast breast dynamic contrast-enhanced MRI

Maya Honda1, Masako Kataoka1, Mami Iima1, Kanae Kawai Miyake1, Akane Ohashi1, Ayami Ohno Kishimoto1, Rie Ota1, Marcel Dominik Nickel2, Tatsuki Kataoka3, Masakazu Toi4, and Kaori Togashi1
1Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 3Department of Diagnostic pathology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Department of breast surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

The study evaluated the accuracy to predict pathologic complete response (pCR) after neo-adjuvant chemotherapy (NAC) using ultrafast dynamic contrast-enhanced (UF-DCE) MRI. The sensitivity to predict pCR was higher on UF-DCE MRI compared with conventional dynamic contrast-enhanced (DCE) MRI. The difference in image and pathological sizes on UF-DCE MRI was smaller than on conventional DCE MRI. UF-DCE MRI potentially assesses post-NAC status in breast cancer patients accurately in a shorter acquisition time.

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