Schizophrenia
is one complex mental disorder. However
the dysregulated cross-network interactions among the SN, CEN and
DMN and how they contributed to different symptoms is still not clear. By
analyzing network interactions among the SN, CEN and DMN in patients
and controls
using DCM,as
well as the relationship
between network dynamics and clinical symptoms,
our
study provides strong evidence for the dysregulation among SN, CEN
and DMN in a triple-network perspective in first-episode schizophrenia. We
further proved that the connection between DMN and CEN could be
clinically-relevant neurobiological signature of schizophrenia symptoms.
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