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Abstract #0916

Gait - related white matter tracts damage in idiopathic normal pressure hydrocephalus

shuai xu1, ye yao2, jing ding3, and he wang*4,5
1Fudan University, Shanghai, China, 2School of Public Health, Fudan University, Shanghai, China, 3Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China, 4Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 5Human Phenome Institute, Fudan University, shanghai, China

Grouping based on white matter hyperactivities (WMH) of each white matter tract, 15 idiopathic normal pressure hydrocephalus (iNPH) patients’ 10 gait index were compared by double sample t test. The results showed some white matter tracts with strongest gait index relationships located in motor and sensory pathways including middle cerebellar peduncle (MCP), left medial lemniscus, left posterior limb of internal capsule and right posterior limb of internal capsule.

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