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Abstract #0918

A correlation analysis between DTI/DKI derived metrics and metabolite levels in the brain of HIV+ individuals

Teddy Salan1, Sameer Vyas2, Paramjeet Singh2, Mahendra Kumar3, Sulaiman Sheriff1, and Varan Govind1
1Radiology, University of Miami, Miami, FL, United States, 2Postgraduate Institute for Medical Education & Research, Chandigarh, India, 3Psychiatry and Behavioral Sciences, University of Miami, Miami, FL, United States

Several studies have focused on diffusion tensor imaging (DTI) as marker for structural damage in the brain due to infection from human immunodeficiency virus (HIV). However, few have associated the findings from diffusion kurtosis imaging (DKI) and magnetic resonance spectroscopic imaging (MRSI) measures. In this work, we correlate measures of DTI and DKI with MRSI in order to evaluate associations between structural alterations and changes in metabolite concentrations within the brain of HIV individuals.

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