Meeting Banner
Abstract #0919

Altered neurometabolic changes in acute mild traumatic brain injury patients: a SPICE study

Tianyao Wang1, Jialin Hu2, Danni Wang2, Yujie Hu2, Jiahua Sun3, Jun Liu1, Yudu Li4,5, Rong Guo4,5, Yibo Zhao4,5, Ziyu Meng2,4, Zhipei Liang4,5, and Yao li2,6
1Radiology department, The Fifth People's Hospital of Shanghai, Shanghai, China, 2Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 3Neurosurgery department, The Fifth People's Hospital of Shanghai, Shanghai, China, 4Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 5Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 6Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China

Mild traumatic brain injury (mTBI) is the most prevalent form of brain injury but the underlying physiological mechanisms are still not fully understood. MRSI has long been recognized as a potentially powerful tool for detection of neurometabolic alterations induced by TBI but most existing studies are limited by low resolution. In this study, we used a 3D high-resolution MRSI technique, known as SPICE, to study neurometabolic alterations in acute mTBI patients. Our experimental results showed various metabolic changes in different areas of patients, which lay a foundation for further investigation to gain new insights into the pathophysiology underlying acute mTBI.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here