Meeting Banner
Abstract #0949

Iopamidol CEST MR Urography for Urinary Tract Obstructions

KowsalyaDevi Pavuluri1, Shaowei Bo1, Farazad Sedaghat1, Max Kates2, and Michael T McMahon1,3
1The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, 3F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Urinary tract obstructions (UTOs) are impairments in urine flow which can lead to pain, infection and irreversible kidney damage if left undiagnosed or untreated. Chemical exchange saturation transfer (CEST) is a novel MRI contrast mechanism that is particularly sensitive to environmental changes including changes in pH values. In this study we developed a protocol by administering the FDA approved iopamidol to obtain dynamic pH and perfusion MRI contrast maps of the kidneys and compared these with iopamidol administered multi-phase CT in a unilateral urinary obstruction mouse model.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here