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Abstract #1162

Osteochondral Junction (OCJ) Imaging Using a Fast T1-weighted 3D Ultrashort Echo Time Cones Sequence at 3T

Zhenyu Cai1,2, Zhao Wei2, Mingxin Chen2, Saeed Jerban2, Hyungseok Jang2, Eric Chang2,3, Jiang Du2, and Yajun Ma2
1Radiology, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, shenzhen, China, 2Radiology, University of California San Diego, San Diego, CA, United States, 3VA San Diego Healthcare System, San Diego, CA, United States

The osteochondral junction (OCJ) is the region where calcified cartilage meets subchondral bone (SCB), and is likely to be highly related to osteoarthritis (OA). However, it is difficult to image OCJ tissues due to their relatively short transverse relaxation times, which cause little or no signal to appear with conventional imaging sequences. In this study, we developed a 3D T1-weighed fast ultrashort echo time cones sequence with fat saturation (FS-UTE-Cones) to generate a high OCJ contrast image of the human knee on a clinical 3T MRI scanner.

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