Very few
MR investigations have been conducted to assess age-dependent myelination differences
in the brainstem, in spite of the brainstem's central role in regulating vital
functions. This is likely due to the small structural scale of the brainstem,
necessitating accurate high spatial resolution imaging for quantitative studies.
Here, we used our recently developed approach to myelin water fraction (MWF)
mapping and found a decrease in myelination with age in different brainstem
regions, with several regions exhibiting a quadratic association. We believe
that this study is the first investigation of MWF changes with normative aging
in the brainstem.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords