To use graph theory approaches and high resolution T1-weighted structural MRI to explore the brain grey matter (GM) morphological network in patients with Parkinson's disease (PD) with and without mild cognitive impairment (MCI). The individual morphological brain networks were constructed by estimating interregional similarity in the distribution of regional GM volume of 116 brain regions. The lower path length were found in both patients relative to healthy controls. Altered morphological connection primarily in default mode network were common deficits, while different connectivity characteristic in widespread regions involving temporal and subcortical regions, and cerebellum were observed between the patient groups.
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