Abstract #1520

Brain Perfusion in Parkinson’s Disease and Multiple System Atrophy using Arterial Spin Labelling MRI

Roshni Kedia¹, Archana Vadiraj Malagi¹, Jitender Saini², and Amit Mehndiratta³

¹Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India, ²Department of Neuroimaging & Interventional Radiology, National Institute of Mental Health and Neuro Sciences, Bengaluru, India, ³Indian Institute of Technology Delhi, New Delhi, India

Absolute perfusion varies in different brain regions for Parkinson’s disease (PD) and Multiple System Atrophy (MSA). These were studied quantitatively using ASL-MRI and the mean perfusion for each brain region was compared. Significant decrease in perfusion was noted for PD compared to healthy subjects for left and right caudate, anterior and posterior cingulate gyrus and occipital fusiform gyrus. For MSA, right caudate showed significant decrease in perfusion compared to healthy subjects.

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