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Abstract #1536

Comparison of interconnected basal ganglia probabilistic tractography between Parkinson's disease patients and controls

Jae-Hyuk Shim1 and Hyeon-Man Baek1
1Gachon University, Incheon, Republic of Korea

Basal ganglia structures, globus pallidus internal, globus pallidus external, subthalamic nucleus, substantia nigra, red nucleus and striatum were automatically segmented on 7T diffusion weighted images of controls and Parkinson's disease patients. Connectivity between each basal ganglia structure was observed using probabilistic tractography generated with FSL's diffusion tools such as BEDPOSTX and PROBTRACKX. Basal ganglia tractography was compared between controls and Parkinson's disease patients to observe the possible changes that could occur in tractography due to Parkinson's disease.

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