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Abstract #1580

Linking priors-assisted Meyer’s loop tractography with visual field deficits in patients undergoing temporal lobe epilepsy surgery

Dmitri Shastin1,2, Sanchita Bhatia2, Chantal M. W. Tax1, Greg Parker1, Stefan Schwartz2, Khalid Hamandi1,2, William Gray2,3, Derek Jones1, and Maxime Chamberland1
1School of Psychology, Cardiff University Brain Research Imaging Centre, Cardiff, United Kingdom, 2School of Medicine, Cardiff University Brain Research Imaging Centre, Cardiff, United Kingdom, 3BRAIN Biomedical Research Unit, Cardiff, United Kingdom

Pre-operative reconstruction of the Meyer’s loop (ML) using diffusion MRI has a clinical utility when planning temporal lobe resection in order to avoid post-operative visual field deficit. Due to its complex anatomy, precise reconstruction of the ML is challenging. Previous literature has suggested that state-of-the-art hardware and tractography using oriented priors better approximates reconstruction to the reported histological prosections. This pilot work evaluates the ability of these improvements to predict visual field deficit in surgical patients. We report a good association in three out of four cases and suggest that simplistic metrics may not necessarily correlate with function.

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