Many tract-based spatial statistics (TBSS) studies in mild traumatic brain injury (mTBI) have been inconsistent. Meanwhile, there is evidence that trauma type may have an effect on white matter (WM) microstructure in mTBI. We performed a tract-based spatial meta-analysis of mTBI and examined the potential effects of trauma type on regional WM microstructure. Our findings identified the left anterior thalamic radiation and right superior longitudinal fasciculus were the most convergent circuitry affected in mTBI and indicated distinct patterns of anatomical connectivity abnormalities in accident related and sport related mTBI, which highlighted the potential importance of trauma specific alterations in mTBI.
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