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Abstract #1591

Feasibility of Dark Blood Susceptibility-Weighted Imaging

Wen-Tung Wang1, Dzung Pham1, and John A Butman1,2
1Center for Neuroscience and Regenerative Medicine, NIH/USU, Bethesda, MD, United States, 2Radiology and Imaging Sciences, NIH, Bethesda, MD, United States

First-order flow compensation has been widely used in MRI. While it works for visualization of vessels and CSF, the residual flow effects can impact the vessels visualization in some applications, such as minimum intensity projection, which is often used in detecting cerebral microhemorrhages on SWI images. When applying minIP, slight offset of spatial registration, and residual flow dephasing from acceleration and pulsatility can manifest as segments of hypointensities, compounding the difficulties in microhemorrhage detection. By including flow sensitization gradients in SWI sequence to suppress flow signal, dark vessels are delineated at correct spatial locations.

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