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Abstract #1651

Measuring blood velocity pulsations in tortuous lenticulostriate arteries:1D versus 3D velocity-encoded imaging at 7T

Marieke van den Kerkhof1,2, Jacobus F.A. Jansen1,2,3, Robert J. van Oostenbrugge2,4,5, and Walter H. Backes1,2
1Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, Netherlands, 2School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands, 3Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 4Department of Neurology, Maastricht University Medical Center, Maastricht, Netherlands, 5Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands

Recently developed 2D phase-contrast sequences showed the feasibility of measuring the small lenticulostriate arteries with 7T MRI. However, these vessels are known to be tortuous, and their tortuosity generally increases with aging and in vascular disease. Therefore, we aimed to measure the blood flow velocity not only in one direction, but in three directions, to capture all three velocity components. We found significant components for the other two, less conventional, velocity directions, which resulted in a lower pulsatility index and peak acceleration when comparing to the 1D measurements.

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