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Abstract #1708

Comparative evaluation of Oligodendroglioma and Astrocytoma subtypes with similar grade using Conventional MRI and T1 perfusion MRI imaging

Mamta Gupta1, Abhinav Gupta1, Anup Singh2, Jitender Saini3, Rana Patir4, Sunita Ahlawat5, Vani Santosh3, Neha Vats2, Manish Awasthi2, Suhail Parvaze6, and Rakesh Kumar Gupta1
1Department of Radiology, Fortis Memorial Research Institute, Gurgaon, India, 2Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi, India, 3National Institute of Mental, Health and Neurosciences, Bangalore, India, 4Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, India, 5SRL Diagnostics, Fortis Remorial Research Institute, Gurgaon, India, 6Philips Innovation Campus, Bangalore, India

The differentiation of oligodendroglioma and astrocytoma has become increasingly important due to the distinct sensitivity of oligodendroglioma (OD) to chemotherapy and prolonged survival compared to astrocytoma (AT) of similar grades. The purpose of the present study was to determine whether unique characteristics of OD and AT are visible on MR imaging and to assess the added value of perfusion imaging in differentiating OD from AT tumors across similar grades in large study population. Our results demonstrated no characteristic/specific conventional MRI features and perfusion parameters those could clearly differentiate similar grades of OD’s and AT tumors.

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