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Abstract #1709

"ASL-CE mismatch": An Imaging Finding for Diagnosis of Brain Tumor, Multicenter Research

Takashi Abe1, Maki Otomo1, Mihoko Kondo1, Yuta Arai1, Yoichi Otomi1, Yuki Matsumoto2, Yuki Kanazawa2, Kohei Nakajima3, Yoshifumi Mizobuchi3, Yasushi Takagi3, and Masafumi Harada2
1Radiology and Radiation Oncology, Tokushima University Hospital, Tokushima, Japan, 2Tokushima University, Tokushima, Japan, 3Neurosergery, Tokushima University Hospital, Tokushima, Japan

One hundred one cases with brain tumor were included (62: HGG, 10: LGG, 18: metastasis, 11: lymphoma), and divided into two groups by the presence or absence of ASL hyperintensity outside of CE area (ASL-CE mismatch). Only the cases with glioma or lymphoma (23 HGG, 7 LGG, 3 lymphoma) revealed ASL-CE mismatch, and the cases with metastasis didn't (p = 0.001). Similar results were obtained in a sub-analysis where data were divided by MRI vendor. This novel finding may reflect tumor invasion and/or vascular growth in the surrounding brain parenchyma, and is useful for identifying metastasis from the other tumors.

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