Abstract #1709

"ASL-CE mismatch": An Imaging Finding for Diagnosis of Brain Tumor, Multicenter Research

Takashi Abe¹, Maki Otomo¹, Mihoko Kondo¹, Yuta Arai¹, Yoichi Otomi¹, Yuki Matsumoto², Yuki Kanazawa², Kohei Nakajima³, Yoshifumi Mizobuchi³, Yasushi Takagi³, and Masafumi Harada²

¹Radiology and Radiation Oncology, Tokushima University Hospital, Tokushima, Japan, ²Tokushima University, Tokushima, Japan, ³Neurosergery, Tokushima University Hospital, Tokushima, Japan

One hundred one cases with brain tumor were included (62: HGG, 10: LGG, 18: metastasis, 11: lymphoma), and divided into two groups by the presence or absence of ASL hyperintensity outside of CE area (ASL-CE mismatch). Only the cases with glioma or lymphoma (23 HGG, 7 LGG, 3 lymphoma) revealed ASL-CE mismatch, and the cases with metastasis didn't (p = 0.001). Similar results were obtained in a sub-analysis where data were divided by MRI vendor. This novel finding may reflect tumor invasion and/or vascular growth in the surrounding brain parenchyma, and is useful for identifying metastasis from the other tumors.

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