Abstract #1774

Difference in Morphometry Measures of 1mm and 0.6mm MPRAGE data with Prospective Motion Correction at 3T

Joelle E. Sarlls¹, Francois Lalonde², Joellyn Stolinski¹, Maxim Zaitsev³, and Lalith Talagala¹

¹NMRF, National Institutes of Health, Bethesda, MD, United States, ²NIMH, National Institutes of Health, Bethesda, MD, United States, ³MR Development and Application Center, University Medical Center Freiburg, Freiburg, Germany

Higher resolution anatomical images can provide more accurate estimates of morphometric measures extracted from segmentation algorithms. Acquisition of submillimeter MPRAGE data at 3T requires long scan times making it prone to subject motion. Prospective motion correction (PMC) techniques can mitigate these effects by tracking brain motion and updating scan parameters accordingly. Here, we compare morphometric measures from 1.0mm and 0.6mm isotropic resolution MPRAGE data obtained at 3T while using PMC. Results show that good quality 0.6mm MPRAGE data can be acquired with PMC in approximately 30minutes. Increased cortical thickness in some brain regions is seen with higher resolution data.

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