Abstract #1967

Association between brain structural alteration and emotional change in depressive patients with suicidal ideation with GQI

Man Teng Cheok¹, Vincent Chin-Hung Chen^2,3, Yuan-Hsiung Tsai⁴, and Jun-Cheng Weng^1,3,5

¹Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan, ²School of Medicine, Chang Gung University, Taoyuan, Taiwan, ³Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan, ⁴Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi, Taiwan, ⁵Medical Imaging Research Center, Institute for Radiological Research, Chang Gung University and Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan

Over 300 million people are suffering from various degrees of depression worldwide. The level of depression severity is a significant risk factor for suicidal behavior. In this study, we used generalized q-sampling imaging (GQI) integrating with clinical diagnostic scale in the suicidal ideation and non-suicidal ideation depressive patients. The multiple regression was performed to identify the association between the GQI indices and the clinical scales. Our results indicated that the demyelination of precuneus may relate to the suicidal ideation in depressive patients.

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