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Abstract #1975

The longitudinal adolescent brain study: subcortical volume correlates of psychological distress in early adolescence

Kathryn Broadhouse1, Amanda Boyes1, Larisa McLoughlin1, Marcella Parker1, Denise Beaudequin1, Gabrielle Simcock1, Jim Lagopoulos1, and Daniel Hermens1
1University of the Sunshine Coast, Sunshine Coast, Australia

Mapping structural trajectories across adolescence provides valuable insights into the “typical” pathway as well as the developmental emergence of mental illness during this dynamic period. Here we present preliminary findings investigating the relationship between the subcortical structures, hippocampus and amygdala (sub-structures known to play important roles in fear pathways and higher order executive functions) and psychological distress measures from the first two time-points in the Longitudinal Adolescent Brain Study. By determining the neuronal changes that present with the psychological symptoms of mental illness, potential efficacious, targeted interventions become a possibility.

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