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Abstract #1976

Resting-state functional neurobiological signatures associated with psychological distress in early adolescence

Kathryn Broadhouse1, Amanda Boyes1, Larisa McLoughlin1, Marcella Parker1, Denise Beaudequin1, Gabrielle Simcock1, Jim Lagopoulos1, and Daniel Hermens1
1University of the Sunshine Coast, Sunshine Coast, Australia

By determining the neuro-functional changes that present with the psychological symptoms of mental illness, potential efficacious, targeted interventions become a possibility. Here we have shown that network dysfunction signatures present in several mental health disorders that underpin emotional regulation and social domain deficits are evident in 12-year-olds with increased psychological distress. Follow-up data from LABS mapping the functional connectome through adolescence and corresponding cognitive and psychological scores will provide valuable insight into the specific neuronal signatures and subsequent divergence pathways that underpin mental health and mental illness.

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