Simultaneous 18F-FDG PET-MR imaging has shown promise for improved diagnostic accuracy of inflammatory cardiac diseases, such as cardiac sarcoidosis. However, respiratory motion and mis-registration between free-breathing 3D PET and conventional 2D breath-held MR images remain a challenge that has hindered clinical adoption of this technique. Here we introduce a 3x-accelerated free-breathing motion-corrected 3D whole-heart T2-mapping prototype sequence, which provides characterisation of myocardial inflammation while additionally providing non-rigid respiratory deformation fields to correct simultaneously acquired PET data. Results from phantom, healthy subjects and patients show that the method produces good-quality high-resolution 3D T2 maps from an efficient scan of ~10 minutes.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords