T2 mapping can be used to effectively detect myocardial edema and inflammation. However, the focal nature of myocardial inflammation may render 2D approaches suboptimal and make whole-heart isotropic 3D mapping desirable. Unfortunately, at 1.5T, self-navigated 3D radial bSSFP results in too noisy images for adequate T2 mapping. In this study, we therefore used a respiratory motion-resolved reconstruction together with image registration to improve the 3D T2 mapping precision and accuracy at 1.5T in patients with inflammatory myocardial injury. The resulting myocardial T2 values matched those of the routine 2D T2 maps, with no discernible bias and slightly lower precision.
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