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Abstract #2127

Quantitative 3D dynamic contrast‐enhanced of Atherosclerosis by using 3D Stack of Star with Golden-angle radial sparse parallel reconstruction

Seong-Eun Kim1, Ye Tian2, Matthew Alexander1, Dennis L Parker1, Gerald S Treiman 3,4, Adam de Havenon5, and J Scott McNally1
1UCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 2Department of Physics and Astronomy, University of Utah, Salt Lake City, UT, United States, 3Department of Surgery, University of Utah, Salt Lake City, UT, United States, 4VASLCHCS, Salt Lake City, UT, United States, 5Department of Neurology, University of Utah, Salt Lake City, UT, United States

Carotid plaque inflammation can be measured with dynamic contrast enhanced (DCE) MRI and is a marker for plaque instability. Increased vascularity, which is one sign of plaque inflammation, can be detected from kinetic analysis of DCE images However, the trade-off between spatial and temporal resolution limits assessment to a small number of slices and ~15 seconds per time frame. To overcome this limitation, we implemented a short-TR 3D T1w Stack of Stars (SoS) sequence to enable retrospective image formation with arbitrary numbers of radial views by using Golden-angle radial sparse parallel (GRASP) reconstruction.

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