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Abstract #2279

A Direct Variational Pressure Estimation Approach for Velocity Data in 4D Flow MRI

Lixing Ren1,2, Xiaowei He2, Dandan Zheng3, and Enhua Wu2,4
1University of Chinese Academy of Sciences, Beijing, China, 2The State Key Lab. of CS, Institute of Software, Chinese Academy of Sciences, Beijing, China, 3Clinical Science, Philips Healthcare, Beijing, China, 4University of Macau, Macau, China

Understanding the nature of the pressure changes is crucial for diagnosis and therapy strategy optimization for aortic aneurysm. 4D flow MRI had offered the opportunity to assess 3D blood flow characteristics. However, the pressure quantification is still a challenge due to the low signal-to-noise ratio and the partial volume effects near the wall. The focus of this work is to address this deficiency by proposing a novel workflow of direct pressure estimation based on simulated noisy 4D flow MRI data.

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