Abstract #2304

Comparison of Capability for Therapeutic Effect Prediction between CEST Imaging and FDG-PET/CT in NSCLC Patients with Chemoradiotherapy

Yoshiharu Ohno^1,2, Masao Yui³, Daisuke Takenaka⁴, Yoshimori Kassai³, Kazuhiro Murayama¹, and Takeshi Yoshikawa²

¹Radiology, Fujita Health University School of Medicine, Toyoake, Japan, ²Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, ³Canon Medical Systems Corporation, Otawara, Japan, ⁴Diagnostic Radiology, Hyogo Cancer Center, Akashi, Japan

No major repots have been evaluated the capability for therapeutic effect evaluation or prediction by chemical exchange saturation transfer (CEST) imaging and compared with FDG-PET/CT. We hypothesized that CEST imaging had equal or better potential for therapeutic effect evaluation and prediction in non-small cell lung cancer (NSCLC) patients with conservative therapy, when compared with FDG-PET/CT. The purpose of this study was to directly and prospectively compare the capability for prediction of therapeutic effect for chemoradiotherapy between CEST imaging and FDG-PET/CT in NSCLC patients.

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