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Abstract #2304

Comparison of Capability for Therapeutic Effect Prediction between CEST Imaging and FDG-PET/CT in NSCLC Patients with Chemoradiotherapy

Yoshiharu Ohno1,2, Masao Yui3, Daisuke Takenaka4, Yoshimori Kassai3, Kazuhiro Murayama1, and Takeshi Yoshikawa2
1Radiology, Fujita Health University School of Medicine, Toyoake, Japan, 2Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 3Canon Medical Systems Corporation, Otawara, Japan, 4Diagnostic Radiology, Hyogo Cancer Center, Akashi, Japan

No major repots have been evaluated the capability for therapeutic effect evaluation or prediction by chemical exchange saturation transfer (CEST) imaging and compared with FDG-PET/CT. We hypothesized that CEST imaging had equal or better potential for therapeutic effect evaluation and prediction in non-small cell lung cancer (NSCLC) patients with conservative therapy, when compared with FDG-PET/CT. The purpose of this study was to directly and prospectively compare the capability for prediction of therapeutic effect for chemoradiotherapy between CEST imaging and FDG-PET/CT in NSCLC patients.

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